Prof. I.V. Premathilake

Professor in Pathology

Department

Department of Pathology

E-mail

ishaprem@yahoo.com

Telephone

Office - +94 11 2758718

Academic Qualifications

  • MBBS / 1994 / Kasturba Medical College Manipal, Mangalore University / India
  • Diploma in Pathology / 2000 / PGIM, University of Colombo / Sri Lanka
  • MD in Histopathology / 2003 / PGIM, University of Colombo / Sri Lanka
  • Consultant Pathologist

Research Interests

  • Mainly gastrointestinal and urological pathology

ORCID ID and Link

https://orcid.org/0000-0001-5323-225X

Google Scholar Link

https://scholar.google.com/citations?user=8lbDhq4AAAAJ

Research Gate Link

https://www.researchgate.net/profile/Isha-Prematilleke

 

Research Grants Held

  • UCARE research grant for research on ‘D-240 staining for lymphovascular invasion in Testicular Seminoma’, Oxford UK 2011, GBP 9000
  • Research grant from the Cancer Research funding of the University of Sri Jayewardenepura, for project titled ‘Incidence of prostate carcinoma in cadaveric prostates in a tertiary care centre in Sri Lanka.’ 2015, Rs. 500,000
  • University of Sri Jayewardenepura research grant for project titled ‘Immunohistochemical Expression of DNA Mismatch Repair Proteins in Colorectal Carcinoma from selected Tertiary Referral Centres in Sri Lanka with Clinicopathological Correlation’. 2022, Rs. 1, 588,300.00

 

Publications and Scientific Communications

Full Articles

National

  • M D S Lokuhetty, I V Premathilake, C Amarasinghe (2002-2003). Epimyoepithelial carcinoma - an uncommon salivary gland tumour. Journal of Diagnostic Pathology, 1, 25-27.
  • Prematilleke, M. Gunawardena, A. Ranasinghe, S. Gunasiri, A Rajapakse. Squamous cell carcinoma of the ampullary region; the pitfalls and challenges in diagnosis. Journal of Diagnostic Pathology 2022;17(1):26-32.
  • Himanshika, D. Samarasinghe, R. Perera, N. Liyanage, M. P. Munasinghe, I. Prematilleke, S. Goonewardena, A. Abeygunasekara. Postpartum urinary incontinence among women attending four postnatal clinics. The Sri Lanka Journal of Surgery 2022; 40(1): 19-22.
  • EW Kosgallana, S Malaviarachchi, S Wijetunge, IV Prematilleke. Histological Evaluation of Tumour Infiltrating Lymphocytes in DNA Mismatch Repair Deficient Colorectal Carcinoma. Review article, Sri Lanka Journal of Cancer 3 (1), 19-26.

International

  • A D Tilakaratna, I Prematilleke, M V C de Silva, (2000).Increase in information content in histopathology reports: a concealed workload for histopathologists. The Malaysian Journal of Pathology 22(1): 21-24
  • I V Prematilleke, V Sujendran, B F Warren, N D Maynard, J Piris (2004) Granular cell tumour of the oesophagus mimicking gastrointestinal stromal tumour on frozen section. Histopathology 44, 502-503.
  • I V Prematilleke, J Piris, K A Shah (2004) Fine needle aspiration cytology of a granular cell tumour of the oesophagus. Cytopathology 15, 120-121
  • D R Warakaulle, I Prematilleke, N R Moore, (2004) Retroperitoneal fibrosis mimicking retrocrural lymphadenopathy. Clinical Radiology 59(3), 292-293
  • Isha Prematilleke, Vivek Mohan, Ian Roberts, Andrew Protheroe, Kevin Gatter (2011) Blastic plasmacytoid dendritic cell neoplasm presenting as a renal mass. Histopathology 59, 799-801.
  • Isha Prematilleke, Olivia Espinosa, Jane Henderson, Paul Altmann, Ian Roberts (2012) Penile calciphylaxis: an unusual cause of penile necrosis. Histopathology 61, 749-750.
  • De Silva WSL, Pathirana AA, Prematilleke I, Rajapakse SAPD, Hettiarachchi PSH, Manawasinghe DS, Dassanayake BK. Two synchronous malignant tumors of the pancreas: a case report. Journal of Medical Case Reports (2017) 11:84.

Presentations with Published Abstracts

National Presentations

  • Prematilleke IV, Faizal MAM, Ratnatunga NVI, Wijekoon ASB. Thymic Hypoplasia with Systemic Fungal Infection in a child - a Case Report. Annual Academic Sessions, Kandy Society of Medicine, 2002 (poster)
  • A N R S Abeysinghe, D H Jayakody, N S Jayasinghe, B M Gunawardana, K I Gunawardena, I V Prematilleke. The Occurrence of Known Risk Factors for Colorectal Carcinoma Among Sri Lankan Patients. Annual Academic Sessions, College of Surgeons of Sri Lanka, 2007. (poster)
  • Prematilleke IV, Senanayake K, Fernando A, Chandrasekera SK. Histological Patterns of Bladder Cancer in a Sri Lankan Tertiary Care Unit. Annual Academic Sessions, College of Pathologists of Sri Lanka, 2008. (poster)
  • Prematilleke IV, Senanayake K, Fernando A, Chandrasekera SK. Histological Patterns of Bladder Cancer in a Sri Lankan Tertiary Care Unit. Annual Academic Sessions, College of Surgeons of Sri Lanka, 2008. (poster)
  • K A D Thilini, K P Wanniarachchi, M D S S Jayathilaka, A G P K Ashoka, I V Premathilleke, D H Beneragama. Use of methyl alcohol and isopropyl alcohol as alternatives to ethyl alcohol in tissue processing. Annual Scientific Sessions of the Faculty of Medical Sciences, University of Sri Jayewardenepura, 07th December 2012. (poster)
  • Rajapakse A, Malewana E, Jayasinghe J, Kailasapathy B, Pathirana A, Prematilleke I. Squamous cell carcinoma of the ampulla of Vater - a case report. Scientific Sessions, Faculty of Medical Sciences, University of Sri Jayewardenepura, 2015. (poster)
  • Prematilleke I, Griffiths C, Cui H, Roberts I. Grading of non-invasive papillary urothelial tumours: evaluation of the Royal College of Pathologists minimum dataset guidelines. Scientific Sessions, Faculty of Medical Sciences, University of Sri Jayewardenepura, 2015. (poster)
  • Medagoda M, Hansika PAM, Prematilleke I. Incidence of needle prick injuries and awareness regarding prevention among third and fourth year medical students. Scientific Sessions, Faculty of Medical Sciences, University of Sri Jayewardenepura, 2015. (poster)
  • De Silva WSL, Pathirana AA, Prematilleke I, Rajapakse SAPD, Hettiarachchi PSH, Manawasinghe DS, Dassanayake BK. Two synchronous malignant tumors of the pancreas: a case report. Scientific Sessions, Faculty of Medical Sciences, University of Sri Jayewardenepura, 2017. (poster)
  • M.T. Chandramali, M.S. Manjika, I.V. Prematilleke. A descriptive analysis of Gleason grades of prostate carcinoma in a tertiary care centre in Sri Lanka. Annual Academic Sesisons, College of Pathologists of Sri Lanka. (poster) Published in: Journal of Diagnostic Pathology 2021;16 (2):55.

International Presentations

  • Prematilleke IV, Abeysinghe ANRS. Prevalence of Known Risk Factors for Colorectal Carcinoma in a Sri Lankan Population. 6th Conference of the Asia Pacific division of the International Academy of Pathology, Kochi, India 2009. (poster)
  • Prematilleke IV, Browning L, Roberts ISD. Multiple subtypes of renal cell carcinoma in end-stage kidneys: a morphological and immunohistochemical study of two cases. 6th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, May 2011, Department of Pathology, University of Ghent, Belgium. (poster)
  • Prematilleke IV, Roberts ISD. Penile calciphylaxis - an unusual cause of penile necrosis. International Conference on Dermatopathology and Uropathology, College of Pathologists of Sri Lanka & British Division, International Academy of Pathology, 2011. (poster)
  • I Roberts, I Prematilleke, C Griffiths, H Cui. Grading of non-invasive papillary urothelial tumours: evaluation of the Royal College of Pathologists minimum dataset guidelines. 26th European Congress of Pathology, 01st September 2014. (poster)
  • Munasinghe MP, Himanshika WAH, Samarasinghe SMD, Perera KPSRY, Liyanage KNR, Prematilleke I, Goonewardena CSE, Abeygunasekara A. Proportion of urinary incontinence and known risk factors among postpartum women in the community and selected tertiary care hospitals in Colombo District, Sri Lanka. International Medical Undergraduate Research Conference, Faculty of Medical Sciences, University of Sri Jayewardenepura, 2019.

Book Chapters Authored

  • Chapter 4: Special Stains. In Handbook on Special Staining Techniques for Workshop for Postgraduate Trainees in Histopathology held at University of Peradeniya, 2000; 06-16
  • Chapter 9: Neoplasia. In Handbook on General Pathology for B.Sc Nursing Students, Faculty of Medical Sciences, University of Sri Jayewardenepura, 2010
  • MLU 1249 - Unit 1: Receiving of Specimens in Histopathology (Session 1 - Specimen handling and reception, Session 2 - Specimen fixation and types of fixatives, Session 3 - Factors affecting the quality of fixation). In Handbook for Medical Laboratory Technology Degree Programme, Open University of Sri Lanka, 2012.
  • MLU 1249 - Unit 10: Troubleshooting in Cytopathology (Session 27 - Technical issues causing diagnostic problems and pitfalls, Session 28 - Quality assurance, Session 29 - Cytopathology audit). In Handbook for Medical Laboratory Technology Degree Programme, Open University of Sri Lanka,
  • Co-author, Volume 4: The importance of correct specimen handling and transport in Histopathology. In National Guidelines, Ministry of Healthcare and Nutrition 2007. ISBN 978-955-9093-43-5.
  • Co-author, Volume 5: Quality control in Histopathology. In National Guidelines, Ministry of Healthcare and Nutrition 2007. ISBN 978-955-9093-43-5.
  • Co-author, Chapter 1, in Collection Handling & Transport of Surgical Specimens, National Guidelines in Histopathology, second edition 2021. ISBN 978-624-6147-03-7

Publications Edited

  • Editor, Conference Proceedings booklet, International Conference on Gastrointestinal Pathology, College of Pathologists of Sri Lanka& British Division, International Academy of Pathology, 2007
  • Editor, Volume 4: The importance of correct specimen handling and transport in Histopathology. National Guidelines and Minimum Datasets, Ministry of Healthcare & Nutrition Sri Lanka, 2007. ISBN 978-955-9093-43-5.
  • Editor, Volume 5: Quality control in Histopathology. National Guidelines and Minimum Datasets, Ministry of Healthcare & Nutrition Sri Lanka, 2007. ISBN 978-955-9093-43-5.
  • Editor, Journal of Diagnostic Pathology, 5(1). Official journal of the College of Pathologists of Sri Lanka. 2011. ISSN 1391-6319
  • Co-Editor, Handbook on General Pathology for B.Sc Nursing Students, Faculty of Medical Sciences, University of Sri Jayewardenepura, 2010
  • Co-editor, National Guidelines in Histopathology, College of Pathologists/Ministry of Health, Sri Lanka, second edition 2021. Volumes included:
    > Carcinoma of the Breast ISBN 978-624-6147-00-6
    > Gynaecological Malignancies ISBN 978-624-6147-02-0
    > Gastrointestinal Tract Tumours ISBN 978-624-6147-01-3
    > Collection Handling & Transport of Surgical Specimens) ISBN 978-624-6147-03-7

 

Research Collaborations

  • Improving detection of lymphovascular invasion in testicular seminoma using D-240 stain. Funded by grant from UCARE, John Radcliffe Hospital Oxford UK 2010-11
  • With university of Peradeniya – project titled ‘Immunohistochemical Expression of DNA Mismatch Repair Proteins in Colorectal Carcinoma from selected Tertiary Referral Centres in Sri Lanka with Clinicopathological Correlation’ 2022 onwards.

 

Awards

  • I V Prematilleke, I S D Roberts. Penile calciphylaxis: an unusual cause of penile necrosis. International conference on Dermatopathology and Uropathology, British Division of the International Academy of Pathology & College of Pathologists of Sri Lanka. Awarded third prize for poster presentation. 2011
  • E W Kosgallana, S Wijetunge, S L Malaviarachchi, G S S Hegoda, I V Prematilleke. Tumour budding and its association with the TNM stage in neoadjuvant treated and untreated colorectal cancers. Annual Academic Sessions, College of Pathologists of Sri Lanka. Awarded third prize for poster presentation. 2023

Other Faculties of University of Sri Jayewardenepura

  • Faculty of Allied Health Sciences

Other Universities

  • University of Oxford UK.
  • General Sir John Kotelawala Defense University
  • Postgraduate Institute of Medicine Colombo
  • University of Colombo
  • University of Kelaniya
  • University of Peradeniya

Awards

  • Award for over 25 years of service to the Faculty 17th December 2023
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