CHRONIC KIDNEY DISEASE OF UNKNOWN AETILOGY IN SRI LANKA

Prof. Kamani Wanigasuriya is conducting research in the field of Chronic Kidney Disease (CKD) with a special interest in the CKD of unknown aetiology in the North Central province of Sri Lanka.
CKD is a major health care problem in the region and is not associated with conventional risk factors. The disease mainly affects males from poor socio-economic backgrounds who are involved in paddy farming. Renal biopsies of these patients were reported as interstitial nephritis raising the concern of possible toxin exposure. The aetiology still remains a mystery. Current research is focused on the urinary biomarkers to identify the disease at a early stage and the urinary excretion of heavy metals in disease and control populations.

Find Out More, Read Her Publications
  1. Chronic kidney disease of unknown aetiology in Sri Lanka: is cadmium a likely cause?  Kamani P Wanigasuriya, Roshini J Peiris-John, Rajitha Wickremasinghe. BioMed Central Nephrology, 2011; 12:32.
    http://www.biomedcentral.com/1471-2369/12/32

  2. Could ochratoxin A in food commodities be the cause of chronic kidney disease in Sri Lanka? Kamani P Wanigasuriya, Hemantha Peiris, Nalaka Ileperuma Roshini J Peiris-John,  Rajitha Wickremasinghe. Transactions of the Royal Society of Tropical Medicine and Hygiene,2008; 102;726-728
    http://www.journals.elsevierhealth.com/periodicals/trstmh/article/S0035-9203(08)00153-3/abstract

  3. Chronic Renal Failure in North Central Province of Sri Lanka, an environmentally induced disease. Kamani P Wanigasuriya, Roshini Peiris-John, Rajitha Wickramasingha, A Hittarage. Transactions of the Royal Society of  Tropical Medicine and Hygiene, 2007; 101:1013-1017

  4. The costs in provision of haemodialysis in a developing country: a multi-centered study. Priyanga Ranasinghe, Yashasvi S Perera, Mohomed FM Makarim, Aruna Wijesinghe, Kamani Wanigasuriya.  BioMed Central Nephrology 2011; 12:42.
    http://www.biomedcentral.com/1471-2369/12/42

  5. Exposure to acetylcholinesterase-inhibitor pesticides and chronic renal failure RJ Peiris-John, JKP Wanigasuriya, AR Wickramasingha, WP Dissanayake A Hittarage. The Ceylon Medical Journal, 2006:51;42-43
    http://www.sljol.info/index.php/CMJ/article/view/1382

  6. Chronic kidney disease of unknown aetiology in the North Central Province of Sri Lanka: trying to unravel the mystery. A R Wickremasinghe, R J Peiris-John, JKP Wanigasuriya. Leading article. Ceylon Medical Journal, 2011;56(4): 143-146
    http://www.sljol.info/index.php/CMJ/article/view/3891

  7. Acute peritoneal dialysis in the National Hospital of Sri Lanka - a study of complications Wanigasuriya JKP, Luckman Hakeem, S D Atukorale, Jenniffer Perera, Rezvi Sherriff.  Journal of the Ceylon College of Physicians 1996:29; 23-26

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