prof-u.g. chandrika

RESEARCH & PUBLICATIONS


 

Prof.  U.G. Chandrika

Prof. U.G. Chandrika B.Sc. (hons), M.Phil., PhD., C.Chem., F.I. Chem.C.

Professor
Department of Biochemistry

Telephone - Office : +94 11 2758000 Ext: 4150     Mobile : +94 71 8252910
E-mail : chandri@sjp.ac.lk, udumalagala2002@yahoo.com


 

GENERAL INFORMATION


 

Education

 

  • Doctor of Philosophy (PhD) in Biochemistry (2004), University of Sri Jayewardenepura, Sri Lanka.
    Thesis title: Content, bioaccessibility, bioavailability and bioconversion of carotenoids in some Sri Lankan fruits and green leafy vegetables.
  • M. Phil in Biochemistry (1999), Massey University, New Zealand.
    Thesis title: Glycosylation of bovine alpha lactalbumin.
  • B.Sc. (Special) Degree in Chemistry (1992) with a second class upper division pass, University of Sri Jayewardenepura, Sri Lanka.

 

 

Working Experience

 

  • July 2011 - to date
    Professor in Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka.
  • March 2008 - July 2011
    Associate Professor in Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka.
  • June 2005 - March 2008
    Senior Lecturer (Grade I) in Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka.
  • June 1999 - June 2005
    Senior Lecturer (Grade II) in Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka.
  • June 1994 - June 1999
    Lecturer in Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka.
  • November 1993 - June 1994
    Demonstrator in Biochemistry, Department of Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka.
  • May 1992 - November 1993
    Assistant Lecturer/Demonstrator in Chemistry, Department of Chemistry, Faculty of Applied Sciences, University of Sri Jayewardenepura, Sri Lanka.

 

 

Current Assignments / Appointments

 

   University of Sri Jayewardenepura, Sri Lanka

  • Head - Department of Biochemistry, Faculty of Medical Sciences (from 2014)
  • Coordinator - Animal House, Faculty of Medical sciences (from 2006)
  • Visiting Lecturer - B.Sc. Special Degree in Botany, Department of Botany, Faculty of Applied Sciences (from 2007)
  • Visiting Lecturer - B.Sc. Special Degree in Zoology, Department of Zoology, Faculty of Applied Sciences (from 200)
  • Visiting Lecturer - M.Sc. in Food Science and Technology, Department of Food Science (from 1999)
  • Examiner of the Aptitude Tests/Promotion Tests for Laboratory Attendants, Technicians (2007 to date)

 

   University of Colombo, Sri Lanka

  • Moderator/External Examiner - B.Sc. Special Degree Program, Department of Botany (from 2009)
  • Visiting Lecturer - Postgraduate Diploma in Toxicology, Department of Forensic Medicine (from 2005)

 

 

Past Appointments

 

   University of Sri Jayewardenepura, Sri Lanka

  • Deputy Director - Staff Development Centre (2005 -2009)
  • Student Counsellor (2003/2005/2006)
  • Co-ordinator - Biochemistry B. Pharm Course (2006 - 2010)
  • Advisor - Biochemistry Specialization (2004-2009)

 

   Eastern University, Sri Lanka

  • External Examiner - B.Sc. Degree Program, Department of Botany (from 2007 to 2010)

 

 

HONOURS & AWARDS


 

  • Presidential awards for research 2007 (Award to authors pursuing research in Sri Lankan institutions for their publications, which have effectively appeared in internationally refereed periodicals, figuring in the Science Citation Index of 2007)
  • Presidential awards for research publication in 2006
  • Presidential awards for research publication in 2005
  • Presidential awards for research publication in 2003
  • Kandiah Memorial award I (2005), for the best piece of research in Chemistry carried out by postgraduate student working in a higher educational Institution
  • Prof. M U S Sulthanbawa award (2004), for the best research paper presented at the Annual Session, Institute of Chemistry, Sri Lanka
  • Award of Fellowship - International Program in the Chemical Sciences for training in "In vitro accessibility studies" Department of Food Science, Chalmers University of Technology, Goteborg, Sweden (2003)
  • Award of Fellowship - International Program in the Chemical Sciences for training in "Carotenoid analysis" at Departmento de Ciencia de Alimentos, Universidade Estadual de Campinas, Campinas, SP., Brasil. (2002)
  • Award of Australian sponsored training scholarship for research training in Biochemistry at University of New South Wales, Australia.(1996)

 

 

MEMBERSHIPS


 

Association Memberships

 

  • Fellow of the Institute of Chemistry, Chartered Chemist (C.Chem, F.I.Chem.C) - Life (from 2000)
  • Vice President and Council member - College of Biochemist of Sri Lanka - Life (from 2013)
  • Member - Sri Lanka Association for the Advancement of Science (SLAAS) - Life (from 1994)
  • Member - Sri Lanka Federation of University Women - Life (from 2000)
  • Member Senior Scientists Forum - NASTEC (From 2000)
  • Member of the Alumni Association University of Sri Jayewardenepura, Sri Lanka (from 2007)
  • Member of the Alumni Association Massey University, New Zealand (From 2004)
  • Member - International Carotenoids Society
  • Member- Nutrition Society of Sri Lanka

 

 

Current Committee Memberships

 

   University of Sri Jayewardenepura, Sri Lanka

  • Member - Senate (from 2011)
  • Member - Curriculum development committee (from 2008)
  • Member - Board of Study Medical Sciences (from 2008
  • Member - Multidisciplinary Board of Study (from 2011)
  • Member - Editorial Board, International Journal of Multidisciplinary Studies (from 2012)
  • Member - Deans Advisory Committee, Faculty of Medical Sciences (From 2008)
  • Co-ordinator - Advance Instrumental Skills and Laboratory Orientation courses - MLS Programme (from 2006)
  • Chairperson - Animal House Committee, Faculty of Medical sciences (from 2006)
  • Chairperson - Metabolism Module, MBBS degree, Faculty of Medical Sciences (from 2010)
  • Convener - Gastro Intestinal Module, MBBS degree, Faculty of Medical Sciences (from 2007)
  • Member - Blood & Immune Module, MBBS degree, Faculty of Medical Sciences (from 2007)
  • Chairperson - Technical Evaluation Committee (Chemicals and lab/medical equipment’s), Faculty of Medical Sciences
  • Member - Research committee, Faculty of Medical Sciences (from 2006)

 

 

Past Committee Memberships

 

   University of Sri Jayewardenepura, Sri Lanka

  • Secretary - Research committee, Faculty of Medical Sciences (2006-2010)
  • Member - Staff Development Committee (2005-2010)
  • Member - Animal House Committee, Faculty of Medical Sciences (2001-2010)
  • Faculty Representative - Research and Publication Committee (2007)
  • Member - 50th Anniversary Celebration Committee (2007)
  • Member - Institutional Review Committee (2006-2011)
  • Member - Quality Assurance Committee (2006-2011)

 

   Eastern University, Sri Lanka

  • External Examiner - B.Sc. degree program in Department of Botany, Eastern University of Sri Lanka.

 

   Institute of Chemistry, Ceylon (Sri Lanka)

  • Assistant Treasurer and Council Member (2004/2005)
  • Member - Workshops Committee (2004/2005)
  • Member - Finance Committee (2004/2005)
  • Member - Monograph Committee (2001/2002)

 

 

FELLOWSHIPS & TRAINING


 

  • ISO/IEC 17025:2005 Training on Development of Quality Manual & Procedures - Sri Lanka Accreditation Board, Colombo, 24-25 March, 2014.
  • 40th International symposium on HPLC 2013, Hobart from 18th - 21st November 2013 at the Hotel Grand Chancellor, Hobart, Tasmania, Australia.
  • ISO 15189 : 2007 Training on Medical Laboratory accreditation-Colombo, 18-19 September, 2012.
  • LC-MS/MS Triple Quad Techniques and Operation - Agilent Customer Training Center, Singapore, 17-19 October, 2012.
  • IUPAB sponsored Workshop - NMR and its applications in Biological System, Tata Institute of Fundamental Research, Mumbai, India, 23-30 November, 2009.
  • The 32nd A-IMBN/AMBO International Training Course on Exploring Structural Biology by Synchrotron Protein Crystallography was held at the Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, September 30 to October 7, 2009.
  • XXII International Vitamin A Consultative Group Meeting in Lima, Peru, 15-17 November, 2004.
  • XXI International Vitamin A Consultative Group Meeting in Marrakesh, Morocco, 3-5 February, 2003.
  • Research training in "In vitro accessibility studies of carotenoids" under the supervision of Prof. ULF Svanberg, Chalmers University of Technology, Gothenburg, Sweden, (Septermber 2003 to February 2004). Fellowship from International Program in the Chemical Sciences, Sweden.
  • Research training in "Carotenoid analysis" under the supervision of Prof. Delia B. Rodriguez-Amaya, Departmento de Ciencia de Alimentos, Universidade Estadual de Campinas, Campinas, SP., Brasil. Experience gained: Carotenoid analysis using OCC, HPLC-DAD (August to December 2002). Fellowship from International Program in the Chemical Sciences, Sweden.
  • "Effective time management for peak performance" University of Sri Jayewardenepura in February 2001.
  • AMBO International Training Course on "Innovative Research strategies for tomorrow: Cell Adhesion, Recognition, Apoptosis and Oxidative stress" at Graduate School of Medicine, Osaka University, Japan. Experience gained: 2-D electrophoresis, Analysis of EGFR and EGF signaling, Analysis of protein glycation (March). 21-28 March, 2001.
  • "Workshop on Learning and teaching", Faculty of Medical Sciences, University Sri Jayewardenepura, 23-25 August 2001.
  • "Leadership excellence and personality development" University of Sri Jayewardenepura in November 2001.
  • "Use of modern Methodologies in Teaching & Research", University of Sri Jayewardenepura in November 2000.
  • M. Phil in Biochemistry, Department of Biochemistry, Massey University, Palmerston North, New Zealand. Courses followed: Research Methods in Biochemistry, Macromolecular Biochemistry, Molecular cell Biology, Nutritional Biochemistry. Experienced gained: Protein purification, electrophoresis, HPLC, FPLC, HPAEC-PAD (1997-1999).
  • Research Training in Biochemistry, School of Biochemistry and Molecular genetics, University of New South Wales, Australia (March - September 1996) - Australian sponsored training scholarship. Experience gained: Enzyme assays, isolation of DNA from garden green pea cultivars, agarose gel electrophoresis, visualization and documentation. DNA purification using RNASE digestion and electro elution, PCR to look for RAPD marker in the pea cultivar.

 

 

RESEARCH GRANTS


 

  • USD 10,000 - International Foundation for Science, Sweden for carotenoids analysis
  • 6.4 Million SLR - National Research Council, Sri Lanka to buy HPLC-DAD system
    Database for carotenoids composition of commonly consumed fruits and vegetables in Sri Lanka (2004-2011)
  • 2 Million SLR - World Class University Project grant (2013-2015)
  • 5 Million SLR - National Research Council, Sri Lanka - Locally developed respiratory care products - University - Private partnership - (Co-grantee and consultant) (2013-2016)

 

 

REVIEWING ACTIVITIES


 

  • British Journal of Applied Science and Technology
  • National Science Foundation - Sri Lanka
  • National Research Council - Sri Lanka
  • NARA Journal
  • International Journal of Multidisciplinary Studies
  • Journal of Taibah University for Science

 

 

RESEARCH & POSTGRADUATE SUPERVISION


 

Postgraduate Supervision Completed

 

  • Ms. P.W.N.M. Colombagama, M.Phil. 2011
  • Thesis title: "Identification and quantification of glucosinolates in local Brassica species/varieties and study of the effect of cooking methods on in vitro accessibility of glucosinolate products
  • Mr. Jagath Wansapala, PhD 2010
    Thesis title: "A study of carotenoids of mango fruits and mango based products and their in-vitro bioavailability"
  • Ms. K.S.U. Perera, M.Sc. 2010
    Thesis title: "Food values in different morphotypes of Centella asiatica L with special preference to iron and calcium content"
  • Ms. M.A.D.V. Chandrapala, M.Sc. 2010
    Thesis title: Carotenoids of different varities of passion fruits
  • Mr. J.M.M.P. Rathnawardhana, M.Sc. 2010
    Thesis title: Varietal differences among the carotenoid profiles of jackfruit varieties studied by HPLC-PDA

 

 

Current Postgraduate Supervision and Ongoing Projects

 

  • Anti-inflammatory compounds from some Sri Lankan medicinal plants (WCUP grant 2013-2015)
    Name of the student: Ms. Kalpani Rathnayake - 1st year MPhil, University of Sri Jayewardenepura Date of registration: 01.07.2013
  • A study of thermal and photochemical degradation of carotenoids (UGC grant 2013-2015)
    Name of the student: Ms. D.D.D.H Alwis - 2nd Year PhD, University of Sri Jayewardenepura
    Date of registration: 01/04/2012
  • Hepatoprotective activity of poly herbal formulation (Funded by Link Natural products (pvt) Ltd.)
    Name of the student: K.A.A.U Karunarathne - 2nd year PhD, University of Sri Jayewardenepura
    Date of registration: 01/01/2012
  • Chemistry and Hypoglyceamic and antioxidant activities Jak (Artocarpus heterophyllus) leaves used in the treatment of diabetes mellitus. Name of the student: Ms. KSSP Fernando - 2nd year MPhil, University of Sri Jayewardenepura (University of Sri Jayewardenepura grant)
    Date of registration: 01/06/2010
  • Development of tea tablet retaining heath properties
    Name of the student: Mrs. Tharangi Rajapaksha - MPhil, University of Sri Jayewardenepura - Thesis submitted
  • Screening endophytes of Nothapodytes nimmoniana for feasible production of camptothecin, an anti-cancer agent
    Name of the student: Ms. K.D. Degambada - 2nd year MPhil, University of Sri Jayewardenepura
    Date of registration: 01/10/2012
  • Screening endophytic microbes from Hylocereus polyrhizus, Ophiorrhiza mungos and Centella asiatica, for the presence of bioactive compounds
    Name of the student: Ms. W.K.C.S. Balawardana - 2nd year MPhil, University of Sri Jayewardenepura (NRC grant)
    Date of registration: 01/01/2012
  • Evaluating C. asiatica morphotypes for high yielding sources of asiaticoside (ASTC) and optimizing conditions for higher yields of ASTC (Funded by Link Natural products (pvt) Ltd.
    Name of the student: Ms. Chathurika - 2nd year MPhil, University of Sri Jayewardenepura
    Date of registration: 01/01/2012
  • Antithrombocytopenic and imunomodulatory activity of selected medicinal plants used in Sri Lanka
    Name of the student: Ms. D.V. Dayangi Hemalika (hoping to register for a Ph.D)

 

 

Undergraduate Research Projects Completed

 

  • Lipid lowering effect of anthocyanin rich extract from Syzygium cumini in a hypercholestrolaemic rat model (2009)
    Name of the student: Ms. Deepani Liyange - B.Sc. Human Biology Biochemistry special
  • Hypocholesterolemic effect of passiflora foetida (2010)
    Name of the student: Ms. Nuwangi Dharmasena, B.Sc. Medical Laboratory Sciences
  • A kinetic study of photodegradation of lycopene in water/acetone solutions (2011)
    Name of the student: Ms. Kalpani Rathnayake, B.Sc. Human Biology Biochemistry special
  • Photochemical degradation of beta carotene in ethanol (2011)
    Names of the students: Ms. L.G.T. Shanika and Ms. J.A.L. Anjalee
  • Photodegradation studies of lycopene in water/acetone solutions (2012)
    Names of the students: Ms. D.D.S. Wijesuriya and A.R. Ekanayake
  • Phytochemistry and antioxidant properties of bixin and norbixin (2013) B.Pharm
    Names of the students: Ms. H.S. Atapattu and Ms. B.B.K. Senanayake

 

 

CONTRIBUTION TO INDUSTRY


 

  • Locally developed respiratory care products - University - Private partnership - (NRC grant (BP 12-18) (2013-2016)

 

 

TEACHING


 

Department of Biochemistry

 

  • MBBS - Phase I and B.Sc. Human Biology - Part I (Foundation/Endocrine/Nutrition/GIT/Blood and Immune modules)
  • B.Sc. Human Biology (Biochemistry/Food and Nutrition) Specialization - Part III - Oganic Spectroscopy (UV, NMR, Mass), Seperation tecniques, supervision of literature review and students' reserch projects, presentation skills
  • B.Sc. Nursing - Part 1- Biochemistry
  • B.Sc. Medical Laboratory Sciences
    - Following Units
    Introduction to Biochemistry, Cell biology, Instrumentation skills I and II, Advanced Instrumentation skills, Human biology III, supervision of literature review and students' reserch projects, presentation skills
  • B.Sc. Pharm - part I and part III (Biochemistry), supervision of literature review and students' research projects

 

 

Other Faculties

 

  • B.Sc. (Special) degree in Botany - Part II (Protein Structure Function, Plant Biochemistry) and Part III (Advanced Plant Biochemistry), supervision of research projects
  • B.Sc. (Special) degree in Zoology - Part III (Nutrion - Food Management)
  • M.Sc. in Food Science and Technology (Advanced Food Biochemistry)

 

 

Outside the University

 

  • Diploma in Toxicology - (Food toxins) - Faculty of Medicine, University of Colombo, Sri Lanka.

 

 

PATICIPATION IN PROFESSIONAL DEVELOPMENT PROGRAM


 

  • Planning of Staff Development Program/ served as a resource person
    As Deputy Director staff Development centre, Following workshops were conducted for the Faculty of Management Studies and Commerce, University of Sri Jayewardenepura (40 participants).
    Educational Technology - 29th and 30th September 2005 at the Sri Lanka Foundation Institute.
    Microteaching - 1st October 2005 at the Lecture hall 1 of the Faculty of Medical Sciences, University of Sri Jayewardenepura.
    Assessments - 16th and 17th December 2005 at the Sri Lanka Foundation Institute.
  • Planning of Staff Development Program/Served as a Resource Person
    Induction training course for the probationary lecturers of the University of Sri Jayewardenepura (19 participants).
    Educational Technology - 27th, 28th July 2006 at the Sri Lanka Foundation Institute.
    Microteaching - 29th July 2006 at the Lecture Hall 2 of the Faculty of Medical Sciences, University of Sri Jayewardenepura.
    Teaching and Assessments and research competencies - 23rd and 24th March 2007 at the Sri Lanka Foundation Institute.
  • Organized and served as resource person for the workshop conducted for the technicians and laboratory attendants on 24th November 2006 at Biochemistry Laboratory, Faculty of Medical Sciences, University of Sri Jayewardenepura.
  • Resource person for the workshop on "Personal Development and Social Harmony" held on the 17/03/2005 for Undergraduates at University of Sri Jayewardenepura.
  • Resource person - NSF/SLAAS Science Forum 2004 - "Studies on Carica papaya carotenoids"

 

 

LIST OF PUBLICATIONS


 

  1. D.D.D.H. Alwis, U.G. Chandrika, P.M. Jayaweera (2014). Spectroscopic studies of neutral and chemically oxidized species of β-carotene, lycopene and norbixin in CH2Cl2: Fluorescence from intermediate compounds. Journal of Luminescence - In Press, Accepted Manuscript-Available online 16 September 2014 (www.sciencedirect.com)
  2. MA Siriwardhene, AM Abeysekera, UG Chandrika, AKE Goonetilleke, (2013) Antihyperglycemic effect and phytochemical screening of aqueous extract of Passiflora foetida (Linn.) on normal Wistar rat model. African Journal of Pharmacy and Pharmacology, 7 (45), 2892-2894.
  3. UG Chandrika, N Salim, GDDJ Wijepala, KSU Perera and AKE Goonetilleke, (2011) Carotenoids and mineral content of different morphotypes of Centella asiatica L. (Gotukola). International Journal of Food Sciences and Nutrition, 62(5): 552-557.
  4. UG Chandrika, AKE Goonetilleke, BMLB Basnayake, I Athukorala and PWNM Colombagama (2010) Carotenoids content and in vitro bio accessibility of lutein in some leafy vegetables popular in Sri Lanka. Journal of Nutritional Science and Vitaminology, 56 (3).
  5. MR Loizzo, R Tundis, UG Chandrika, AM Abeysekera, F Menichini, NG Frega, F Menichini (2010). Antioxidant and antibacterial activities on food borne pathogens of Artocarpus heterophyllus Lam. (Moraceae) leaves extracts. Journal of Food Science, 75 (5): M291-M295.
  6. UG Chandrika, KSSP Fernando, KKDS Ranaweera (2009). Carotenoids content and in vitro bio accessibility of lycopene from guava (Psidium guajava) and watermelon (Citrullus lanatus) by HPLC-DAD. International Journal of Food Sciences and Nutrition, 60 (7): 558-566.
  7. UG Chandrika (2009), Carotenoid Dyes - Properties Handbook of Natural Colorants, Publisher John Wiley and Sons Ltd, UK, 221-
  8. UG Chandrika (2009), Factors Influencing Carotenoid Composition in Plant Sources Handbook of Natural Colorants, Publisher John Wiley and Sons Ltd, UK, 237-
  9. Wickramasinghe I, Ranaweera KKDS, Chandrika UG, Bamunuarchchi A (2008) Content and in vitro availability of iron in cooked fish commonly consumed Sri Lanka. Journal of National Science Foundation. 36 (4): 327-330.
  10. AMB Priyadarshani, UG Chandrika (2007). The carotenoids of some selected Sri lankan non-leafy vegetables. Journal of National Science Foundation. 35 (4): 251-253.
  11. AMB Priyadarshani and UG Chandrika (2007) Content and in-vitro accessibility of pro-vitamin A carotenoids from Sri Lankan cooked non-leafy vegetables and their estimated contribution to vitamin A requirement. International Journal of Food Science and Nutrition, 58 (8): 659-667.
  12. TMJC Madatuwa, STC Mahawithanage, UG Chandrika, ER Jansz et al (2007) Evaluation of the effectiveness of the national vitamin A supplementation programme among school children in Sri Lanka. British journal of nutrition, 97 (1): 153-159.
  13. Mahawithanage STC, Kanangara KKNP, Wickramasinghe R, Chandrika UG, Jansz ER, Karunaweera, ND and Wickramasinghe, AR (2007). Impact of vitamin A supplementation on health status and absenteeism of school children in Sri Lanka. Asian pacific Journal of the Clinical Nutrition, 16 (1): 94-102.
  14. Chandrika UG, Wedage WS, Wickramasinghe SMDN and Fernando WS (2006). Hypoglycaemic activity of flavonoid fraction of Jack (Artocarpus heterophyllus) leaves. African Journal of Traditional and Complementary Medicine, 3 (2): 42 - 50.
  15. Madatuwa, TMJC, Mahawithanage, STC, Chandrika UG, Jansz, ER and Wickremasinghe, AR (2006) Evaluation of the effectiveness of the national Vitamin A supplementation program among school children in Sri Lanka. British Journal of Clinical Nutrition, 97 (1): 153-9.
  16. Chandrika UG, Svanberg, U. and Jansz, ER (2006). Content and in vitro accessibility of beta-carotene from cooked Sri Lankan green leafy vegetable and their estimated contribution to vitamin A requirement. Journal of the Science of Food and Agriculture, 86 (1): 54 - 61.
  17. Chandrika, UG, Wedage, WS.,Wickramasinghe SMDN and Fernando (2006). Hypoglycaemic activity of flavonoid fraction of Jack (Artocarpus heterophyllus) leaves. African Journal of Traditional and Complementary Medicine, 3 (2): 42 - 50.
  18. Chandrika UG, Jansz, ER, and Warnasuriya, ND (2005) Analysis of carotenoid composition of ripe jakfruits (Artocarpus heterophyllus) kernel and its Bioconversion. Journal of the Science of Food and Agriculture, 85: 186 - 190.
  19. Chandrika UG, Jansz ER and Warnasuriya, ND (2005). Analysis of β-carotene and lutein in some leafy vegetables and effect of cooking on serum vitamin A formation from Alternanthera sessilis. Journal of National Science Foundation Sri Lanka, 33 (2): 141-145.
  20. Chandrika UG, Jansz, ER and Warnasuriya, ND (2005).Identification and HPLC quantification of carotenoids of the fruit pulp of Chrysophyllum roxburgi. Journal of National Science Foundation Sri Lanka, 33 (2): 93-98.
  21. Chandrika UG (2005) Purification and partial characterisation of Glycosylated bovine alpha lactalbumin. Vidyodaya Journal of Science, 12:71-76.
  22. Jayaweera, PM, Chandrika UG, and Jansz, ER (2004) Computational evidence for the reactive non electrostatic hydrophobic binding of beta-sitosterol with acyclic carotenes. Institute of Chemistry in Sri Lanka, 22 (2): 26-27.
  23. Chandrika UG (2004) Content, bioavailability, bioconversion and antioxidant activities of carotenoids in some Sri Lankan fruits and green leafy vegetables. University of Sri Jayewardenepura: USJ (MED).
  24. Chandrika UG, Jansz ER, Wickramasinghe SMDN and Warnasuriya, ND (2003). Carotenoids in yellow and red-fleshed papaya. Journal of the Science of Food and Agriculture, 83 (12): 1279 - 1282.
  25. Chandrika UG, Jansz, ER, Wickramasinghe, SMDN and Warnasuriya, N. (2003). Bioconversion of pro-vitamin A carotenoids and antioxidant activities of Carica papaya fruits. Journal of National Science Foundation Sri Lanka, 31(3&4): 437- 444.
  26. Chandrika UG, Norris GE (2000) Comparsion of analytical techniques for separation of N-linked oligosaccharides in a model glycoprotein (ribonuclease B). Journal of Science Eastern University of Sri Lanka, 2(1): 35-41.
  27. Chandrika UG (2001) Non-covalently attached hexosamine-hexose of bovine alpha lactalbumin. Journal of Science Eastern University of Sri Lanka, 2 (1): 35-41.
  28. Mahatantila, K.C. and Chandrika U.G., (1998). Chemical Investigation of Jack (Artocarpus heterophyllus) leaves used in the treatment of diabetes mellitus. Ayurveda Sameekshawa, 50: 243 - 245.

 

 

Manuscripts Submitted

 

  1. Chandrika UG, Sri Lankan Database on food carotenoids. Journal of the Science of food and Agriculture
  2. D.D.D.H. Alwis, U.G. Chandrika, P.M. Jayaweera (2014). UV light induced photo-degradation study of carotenoids in MeOH: The influence of inorganic anions. - International Journal of Multidisciplinary studies
  3. K.A.A.U. Karunarathana, A.M. Abeysekera, U.G. Chandrika, B. Senevirathna, C. Padumadasa and T.M.S.G. Tennakoon (2014) Safety evaluation of a new hepatoprotective polyherbal formulation in ICR male mice - International Journal of Multidisciplinary studies

 

 

Anuscripts in Preparation

 

  1. Chandrika UG and Fernando KSSP - Prolycopene from Borassus flabillifer fruit
  2. PWNM Colombagama, KKDS Ranaweera and UG Chandrika Content and in vitro accessibility of Glucosinolates in Sri Lankan Brassicaceae family vegetables
  3. Liyanage PLDW, Chandrika UG Lipid lowering effect of anthocyanin rich extract form Syzygium cumini on a hypercholesterolaemic rat model.
  4. MAJ Wansapala, U.G. Chandirka, KKDS Ranaweera, A. Bamunuarchchi Content and in vitro accessibility of mango based products.
  5. Ophiorrhiza mungos: a significant source of camptothecin - an anticancer agent.

 

 

Scientific Communications

 

  1. K.D. Degambada, N. Salim, U.G. Chandrika, A. M. Abeysekera and S. Wijesundara. Distribution and content of camptothecin, an anti-cancer agent in Nothapodytes nimmoniana of Sri Lankan origin (accepted for YSF Symposium - 2014)
  2. Chandrika U Gamage, Nilanka M Colombagama, KKDS Ranaweera (2013). Identification and quantification of Glucosinolates in Sri Lankan Brassicaceae family vegetables. 40th International symposium on HPLC 2013, 18 -21 November 2013 at the Hotel Grand Chancellor, Hobart, Tasmania, Australia.
  3. D.D.D.H. Alwis, U.G. Chandrika and P.M. Jayaweera (2013) Absorption and Emission Properties of Lycopene, β-Carotene, Norbixin and their Chemically Oxidized Species, Chemistry in Sri Lanka, 30 (2): 13
  4. A.M. Abeysekara, KAAU Karunarathna, U.G. Chandrika and B. Seneviratne, C. Padumadasa and TMSG Tennakoon (2013). Hepato-protective activity of a poly herbal formulation against
    CCl4 induced acute hepatotoxicity in ICR mice. Sri Lanka Association for the advancement of Science, Proceedings of the 69th Annual session - Part 1, page 151.
  5. Wanigasuriya K, Chandrika U.G., Goonarathne J., Herath C., Perera P.P.R., Wijayatunga N.N. (2013). Abnormal serum retinol and α tocopherol levels in a sample of Sri Lankan patients on regular hemodialysis. Annual sessions of Nutrition Society of Sri Lanka 2013.
  6. Fernando KSSP, Abeysekera AM, Chandrika UG, Goonathilake AKE, Padumadasa C., Hypoglyceamic and antioxidant activities of fractions obtained from the ethyl acetate fraction of water extract of Artocarpus heterophyllus leaves". International Conference on Chemical Sciences, 20-22 June 2012, Sri Lanka Foundation Institute, Colombo 7, Page 85.
  7. T.S. Guruge, L.A. Jayaweera, U.G. Chandrika and P.M. Jayaweera (2012). A Kinetic Study of Photodegradation of β-Carotene in Water/Ethanol Solutions. International Conference on Chemical Sciences, 20-22 June 2012, Sri Lanka Foundation Institute, Colombo 7, Page 120.
  8. D.D.D.H. Alwis, W.M.K.M. Ratnayake, U.G. Chandrika, P.M. Jayaweera. (2012). A Kinetics study of photodegradation of lycopene in water/acetone solutions. Proceeding of the Sri Lanka Association for the Advancement of Science.
  9. Salim, N., Chandrika U.G, Abeysekera, A.M and Senanayeka, S.M.C (2011)
    Microbial production of a plant alkaloid, camptothecin: a promising anticancer agent-(201I)-Proceedings of the IFS-IFASSA - International Symposium on Natural product and their applications in health and agriculture, IFS, Kandy, Sri Lanka (3-8 October 2011) -page 94.
  10. G.A. Ranasinghe, N. Salim, U.G. Chandrika, A.M. Abeysekera (2011) Accumulation of camptothecin (CPT) in Ophiorrhiza mungos L and the influence of climatic conditions on CPT content Proceedings of the Sri Lanka Association for the advancement of Science, 67(1) 44.
  11. G.A. Ranasinghe, N. Salim, U.G. Chandrika, A.M. Abeysekera (Sri Lanka) Efficacy of Two Different Methods of Extraction of Camptothecin from Ophiorrhiza mungos-(201I) Proceedings of the IFS-IFASSA - International Symposium on Natural product and their applications in health and agriculture, IFS, Kandy, Sri Lanka (3-8 October 2011)-page 62.
  12. M.A. Siriwardhene, A.M. Abeysekera, U.G. Chandrika, A.K.E. Goonetilleke (Sri Lanka. Hypoglycemic and hypolipidemic effects of the methanolic extract of Costus speciosus (Koen) Sm., leaf extract in Alloxan-induced diabetic rats-(201I)-Proceedings of the IFS-IFASSA - International Symposium on Natural product and their applications in health and agriculture, IFS, Kandy, Sri Lanka (3-8 October 2011) - page 68.
  13. Abeysekera AM, Mudalige, TSR, Chandrika UG, Goonetilleke AKE (2011). Comparison of the antioxidant potential of a cup of instant black tea with that of an organoleptically equivalent cup of brewed black tea Chemistry in Sri Lanka, 28(2): 19.
  14. Perera KSU, Salim N, Chandrika UG (2010). Food values in different morphotypes of Centella asiatica L. (Gotukala) with special preference to mineral content. Proceedings of the Sri Lanka Association for the advancement of Science, 66 (1): 75.
  15. Liyanage PLDW, Chandrika UG (2010). Lipid lowering effect of anthocyanin rich extract from Syzygium cumini in a hypercholestrolaemic rat model. Annual Scientific Sessions, Faculty of Medical Sciences, University of Sri Jayewardenepura. 2010, 11-12 December 2010: OP14.
  16. Abeysekara, AM, Chandrika UG, Gunaherath GMKB and Ranasinghe C. (2009). Ayurvedic medicinal oils: octanol-water partition coefficients of some compounds found in "Pinda" oil. Proceedings of the Sri Lanka Association for the advancement of Science, 65 (1): 131.
  17. Wansapala, MAJ, Chandrika UG, Ranaweera KKDS and Bamunuarchchi A (2009) Content and in vitro bio-accessibility of β -carotene from three mango fruit varieties 50th Anniversary Academic conference,11-12 December 2009, University of Sri Jayewardenepura.
  18. Senanayake SMC, Salim, N, Chandrika UG and Abeysekara AM (2009). Isolation of an endophytic fungus from Ophiorhiza mungos L. (Rubiaceae), producing camptothecin, an anticancer agent. Proceedings of the Sri Lanka Association for the advancement of Science, 65 (1): 95.
  19. Chandrapala MADV and Chandrika UG Identification of carotenoids from yellow passion fruits found in Sri Lanka (2008). Proceedings of the Sri Lanka Association for the advancement of Science, 64 (1).
  20. Wansapala, MAJ, Chandrika UG, Ranaweera KKDS and Bamunuarchchi A (2008) Content and in vitro bio-accessibility of β -carotene from two mango fruit varieties. Proceedings of the Sri Lanka Association for the advancement of Science, 64 (1).
  21. Wickramasinghe, I., Ranaweera, KKDS., Chandrika UG, Bamunuarchchi, A. and Wijesinghe I. D., (2007) Iron content and in vitro iron availability in cooked Sardinella melanura (salaya) and Caranx spp. "International Conference on Tropical Aquatic research towards Sustainable Development", 15th-16th February 2007 in Colombo, Sri Lanka.
  22. Wansapala, MAJ, Chandrika UG, Ranaweera, KKDS and Bamunuarachchi A. (2007) Extraction, Separation and identification of karthacolamban mango fruit carotenoids Institute of Chemistry, Chemtech 2007, Colombo, Sri Lanka, page 62
  23. Wickramasinghe, I., Ranaweera, KKDS., Chandrika UG, Bamunuarchchi, A. and Wijesinghe I. D., (2007) iron content and in vitro availability in cooked Sardinella melanura, Sadinella albella, Carnax spp. and Exocoetus volitans Food the Challenges NZIFST conference 2007, Wellington, NZ 9-21, June.
  24. Fernando KSSP, Chandrika UG. And Ranaweera KKDS (2007). Cantaloupe Melon as a Solution for Vitamin A Deficiency. Sri Lanka Association for the advancement of Science,63(1): 202.
  25. Fernando KSSP, Chandrika UG. and Ranaweera KKDS(2007). Red fleshed guava as source of lycopene. Proceedings of the Sri Lanka Association for the advancement of Science, 63 (1): 203.
  26. Wickramasinghe, I, Ranaweera, KKDS, Chandrika UG and Bamunuarchchi A (2007) Content and in vitro availability of iron in cooked Kowala coval and Exocoetus volitans. Proceedings of the Sri Lanka Association for the advancement of Science, 63 (1): 42.
  27. Priyadarshani, AMB, and Chandrika UG (2006). Effect of cooking methods on the in vitro accessibility of carotenoids of yellow-fleshed sweet potatoes found in Sri Lanka. Bioavailability 2006, 7-10 March 2006, Chiang Mai, Thailand.
  28. Edirisinghe, EARI and Chandrika UG (2006). Content and in vitro accessibility of lycopene from Watermelon. Chemistry in Sri Lanka, 9 (2): 23.
  29. Fernando KSSP, Chandrika UG and KKDS Ranaweera (2006) Carotenoids from two different varieties of emberella (Spondias ceytherea and Sphondias dulcis). Proceedings of the Sri Lanka Association for the advancement of Science, 62 (1) : 200.
  30. Colombagama, PWNM, Chandrika UG and Ranaweera KKDS (2006) Identification and quantification of carotenoids of Welkohila leaves (Syngonium angustatum). Proceedings of the Sri Lanka Association for the advancement of Science, 62(1): 112.
  31. Colombagama, PWNM, Ranaweera, KKDS, Chandrika UG (2006) Study of Nutritional quality changes of blast frozen pitasudusarana (Boerhavia diffusa) 5th Annual Academic Sessions, Faculty of Medical Sciences, University of Sri Jayewardenepura. 2007, 18-19 January 2007, 8.
  32. Priyadarshani, AMB., Chandrika UG and Jansz, ER. (2005). In vitro accessibility of pro-vitamin A carotenoids from cooked carrots (Daucus carota) and their estimated contribution to vitamin A requirement. Chemistry in Sri Lanka, 22 (3): 22.
  33. Priyadarshani, AMB, Chandrika UG, and Jansz, ER. (2005). Carotenoid content of different pumpkin (Cucurbita maxima) varieties found in Sri Lanka. International Symposium on Herbal Medicine, Phyto-pharmaceuticals and other natural products: Trends and Advances - I. Chem C & NASTEC. 43.
  34. Weerasekara, DBCR, Mahawithanage, STC., Chandrika UG. (2005). A preliminary study on zinc status and selected pregnancy outcomes of early pregnant mothers. 03rd Symposium on Food and Nutrition, Wayamba University, Sri Lanka.
  35. Chandrika UG. (2005). Content, Bio accessibility, Bioavailability and Bioconversion of carotenoids in some Sri Lankan fruits and green leafy vegetables. Chemistry in Sri Lanka, 22 (1) : 15 - 17.
  36. Chandrika UG, and Jansz, ER. (2004). Carotenoid composition of Lavalu. Chemistry in Sri Lanka, 21 (2): 19.
  37. Chandrika UG and Jansz, ER (2004). Identification and HPLC Quantification of beta-carotene and lutein in some green leafy vegetables commonly used in Sri Lanka. Chemistry in Sri Lanka, 21 (2): 20.
  38. Jayaweera, PM, Chandrika UG and Jansz ER. (2004). Computational evidence for the reactive non electrostatic hydrophobic binding of beta-sitosterol with acyclic carotenes. Chemistry in Sri Lanka, 21 (2):26.
  39. Chandrika UG., Svanberg, U. and Jansz, ER. (2004). Content and in vitro accessibility of beta-carotene cooked green leafy vegetables from Sri Lanka. Report of the XX1I International Vitamin A Consultative Group Meeting in Peru, 15-17 November 2004: 30
  40. Mahawithanage, STC., Chandrika UG., Wickramasinghe, AR. and Karunaweera, ND. (2004). Impact of vitamin A supplementation on health status and absenteeism of school children in Sri Lanka. Report of the XX1I International Vitamin A Consultative Group Meeting in Peru, 15-17 November 2004: 70
  41. Madatuwa, TMJC, Mahawithanage STC., Chandrika UG and Wickramasinghe, AR (2004). Evaluation of the national vitamin A supplementation program in school children in rural areas of Sri Lanka. Report of the XX1I International Vitamin A Consultative Group Meeting in Peru, 15-17 November 2004: 70
  42. Chandrika UG, Wedage WS., Wickramasinghe SMDN. and Fernando, WS. (2004). Hypoglycaemic action of the flavonoid fraction of jack leaves Artocarpus heterophyllus). Second Global Summit on Medicinal and Aromatic plants. October 25-29, 2004, New Delhi, India.
  43. Chandrika UG, Jansz, ER., Wickramasinghe, SMDN. And Warnasuriya, ND. (2003) Carotenoid composition of ripe jack fruits (Artocarpus heterophyllus). Chemistry in Sri Lanka, 20 (2) : 8.
  44. Chandrika UG., Jansz, ER., Wickramasinghe, SMDN. and Warnasuriya, ND. (2003). Studies on bioavailability and bioconversion of papaya (Carica papaya) carotenoids. Report of the XX1 International Vitamin A Consultative Group Meeting in Morocco, 3-5, February 2003 : 68
  45. Chandrika UG, Fernando, WS., Wickramasinghe SMDN. and Wedage, WS. (2002). Anti-diabetic and antioxidant activities of Jack (Artocarpus heterophyllus) leaves. Proceedings of the Sri Lanka Association for the advancement of Science, 58 (1): 249.
  46. Ekanayake, S. and Chandrika UG (2002). Antioxidant and hypocholestrolemic activities of palmyrah (Borassus flabillifer L) fruit. Proceedings of the Sri Lanka Association for the advancement of Science, 58 (1): 4.
  47. Chandrika UG, Jansz, ER. And Uduwaluge., I. (2002). Preliminary bioavailability trials of carotenoids from palmyrah (Borassus flabelifer L.) fruit pulp in a healthy, male Wistar rats. Chemistry in Sri Lanka, 19 (2): 19 - 20.
  48. Chandrika UG, Fernando, WS., Wickramasinghe, SMDN. and Wedage, WS. (2002). Effects of Proanthocyanidin and Flavonoid fractions from hot water extract of Jack leaves (Artocarpus heterophyllus) on the blood glucose levels in healthy, male Wistar rats. Chemistry in Sri Lanka, 19 (2):10.
  49. Samarasinghe, I., Chandrika UG. And Jansz, ER. (2001). Some studies on the carotenoids and flabelliferins of Palmyrah fruit pulp. Proceedings of the Sri Lanka Association for the advancement of Science, 57 (1): 253.
  50. Chandrika UG, Jansz, ER., Wickramasinghe, SMDN and Warnasuriya, ND. (2001). Separation, identification, and Quantification, of carotenoids of two major varieties of Carica papaya grown in Sri Lanka using MPLC. Proceedings of the Sri Lanka Association for the advancement of Science, 57 (1): 254.
  51. Chandrika U.G. and Norris, G.E. (2000). Glycosylation of bovine alpha lactalbumin. Chemistry in Sri Lanka, 17 (1) : 6
  52. Nikawala, J.K., Jansz, E.R., Wijerathne, S.C., Abeysekara, A.M., and Gamage, U.C., (1998). Studies on chemistry and bioactivity of the flabelliferins, steroidal saponins from palmyrah (Borassus flabellifer L.). Chemistry in Sri Lanka, 15 (1): 6.
  53. Mahatantila, K.C., Chandrika U.G., (1994). Chemical Investigation of Jack (Artocarpus heterophyllus) leaves used in the treatment of diabetes mellitus. Proceedings of the Sri Lanka Association for the advancement of Science, 50: 261 - 262.