dr-p.h.k.i.s. ranasinghe

RESEARCH & PUBLICATIONS


 

Dr.  P.H.K.I.S. Ranasinghe

Dr. P.H.K.I.S. Ranasinghe

Senior Lecturer Grade I and Head
Department of Parasitology

Telephone - Office : +94 11 2758679     
E-mail : ishalindra@yahoo.com

Google Scholar >>


 

PUBLICATIONS ON LEISHMANIASIS


 

  1. McCall LI, Zhang WW, Dejgaard K, Atayde VD, Mazur A, Ranasinghe S, Liu J, Olivier M, Nilsson T, Matlashewski G (2015). Adaptation of Leishmania donovani to Cutaneous and Visceral Environments: in Vivo Selection and Proteomic Analysis. J Proteome Res. 14:1033-59.
  2. Zhang WW, Ramasamy G, McCall LI, Haydock A, Ranasinghe S, Abeygunasekara P, Sirimanna G, Wickremasinghe R, Myler P, Matlashewski G (2014) Genetic analysis of Leishmania donovani tropism using a naturally attenuated cutaneous strain. PLoS Pathog. 10:e1004244.
  3. Ranasinghe S, Wickremasinghe R, Munasinghe A, Hulangamuwa S, Sivanantharajah S, Seneviratne K, Bandara S, Athauda I, Navaratne C, Silva O, Wackwella H, Matlashewski G, Wickremasinghe R (2013) Cross-Sectional Study to Assess Risk Factors for Leishmaniasis in an Endemic Region in Sri Lanka. Am J Trop Med Hyg. 89:742-9.
  4. Ranasinghe S, Zhang WW, Wickremasinghe R, Abeygunasekera P, Chandrasekharan V, Athauda S, Mendis S, Hulangamuwa S, Matlashewski G, Pratlong F (2012) Leishmania donovani zymodeme MON-37 isolated from an autochthonous visceral leishmaniasis patient in Sri Lanka. Pathog Glob Health. 106: 421-4.
  5. McCall LI, Zhang WW, Ranasinghe S, Matlashewski G (2013) Leishmanization revisited: Immunization with a naturally attenuated cutaneous Leishmania donovani isolate from Sri Lanka protects against visceral leishmaniasis. Vaccine. 31:1420-5.
  6. Ranasinghe S, Maingon RD, Bray DP, Ward RD, Udagedara C, Dissanayake M, Jayasuriya V, de Silva NK (2012) A morphologically distinct Phlebotomus argentipes population from active cutaneous leishmaniasis foci in central Sri Lanka. Mem Inst Oswaldo Cruz. 2012; 107: 402-9.
  7. Ranasinghe PHKIS, Abeygunasekera PH, Athauda SB, Chandrasekharan NV, Mendis AVS, Hulangamuwa CS, Wickremasinghe DR (2011) First successful in vitro culture of Leishmania sp. causing autochthonous visceral leishmaniasis in Sri Lanka. Ceylon Med J.56: 179-80. doi: 10.4038/cmj.v56i4.3904.
  8. Ranasinghe S, Rogers ME, Hamilton JG, Bates PA, Maingon RD (2008) A real-time PCR assay to estimate Leishmania chagasi load in its natural sand fly vector Lutzomyia longipalpis. Trans R Soc Trop Med Hyg. 102: 875-82.

 

 

COMMUNICATIONS ON LEISHMANIASIS


 

  1. Peduru Shalindra Ranasinghe, Rajitha Wickremasinghe, Asoka Munasinghe, Sanjeeva Hulangamuwa, Kamal Seneviratne, Samantha Bandara, Indira Athauda, Chaturi Navaratne, Ositha Silva, Hasini Wackwella, Greg Matlashewski, Renu Wickremasinghe 2013. Early pattern of rk39 sero-prevalence in a cutaneous leishmaniasis endemic area in Sri Lanka. The fifth world congress on leishmaniasis - worldleish5. P- 670.
  2. Peter J Myler, Gowthaman Ramasamy, Maowia Mukhtar, Greg Matlashewski, Wen Wei Zhang, Shalindra Ranasinghe, and Carlos Costa (2013) Comparative genomics of Leishmania isolates from Africa, Asia and South America. 5th International congress on leishmaniasis-WorldLeish5. O-349.
  3. Laura-Isobel McCall, Wen-wei Zhang, Shanlindra Ranasinghe, Greg Matlashewski (2013) Live immunization against visceral leishmaniasis: immunization with a naturally attenuated cutaneous leishmania donovani isolate from Sri Lanka protects against visceral disease The fifth world congress on leishmaniasis - worldleish 5 O-155
  4. Shalindra Ranasinghe, Rajitha Wickremasinghe, Asoka Munasinghe, Sanjeeva Hulangamuwa, Kamal Seneviratne, Samantha Bandara, Indira Athauda, Chaturi Navaratne, Ositha Silva, Hasini Wackwella, Greg Matlashewski, Renu Wickremasinghe (2012) A cross sectional study to assess the socio-demographic risk factors for transmission of leishmaniasis in an endemic region of Sri Lanka. Theoretical and Practical Course on "Molecular Biology of Leishmania" ICGEB, Trieste, Italy. PP 17.
  5. Shalindra Ranasinghe, Sanjeeva Hulangamuwa, Rhayza Maingon, Opatha Nandimitra, Renu Wickremasinghe, Vishvanath Chandrasekharan (2012). Detection of Leishmania DNA in skin biopsy samples using DNA based methods in Sri Lanka. Theoretical and Practical Course on "Molecular Biology of Leishmania" ICGEB, Trieste, Italy. OP.
  6. PHKIS Ranasinghe, JGC Hamilton, ME Rogers, PA Bates, RDC Maingon (2005) A real-time PCR assay to quantify Leishmania within sandflies. 5th International Symposium on Phlebotomine sandflies. OP-33.
  7. PHKIS Ranasinghe, ME Rogers, PA Bates, JGC Hamilton, RDC Maingon (2005) Development of a highly sensitive QRT-PCR method to quantify the Leishmania infantum load within its natural vector Lutzomyia longipalpis. The Bulletin of the Sri Lanka College of Microbiologists. OP 16.

 

 

GUIDELINES PREPARATION ON LEISHMANIASIS


 

  1. Sirimanna GMP, Seneviratne JKK, Samaraweera ESN, Ranawaka RR, Hulangamuwa CS, de Silva VNH, Madarasinghe NP, Ranasinghe S, Silva KKMBK, Chandrawansa PH, Ariyawansa DS (2013). Guidelines on management of leishmaniasis. Sri Lanka College of Dermatologists. ISBN 978-955-0326-02-0

 

 

SYMPOSIUM LECTURES ON LEISHMANIASIS


 

  1. Symposium Lecture: conducted on "Laboratory diagnosis of leishmaniasis" Symposium organized by the Communicable Disease Committee of the Sri Lanka Medical Association 22nd Nov 2013.
  2. Symposium Lecture: Emerging infections-Leishmaniasis. Faculty of Medical Sciences, University of Sri Jayewardenepura, Annual Scientific Sessions 2010

 

 

POSTGRADUATE AWARDS, GRANTS & TRAINING


 

  1. Wellcome Trust & NSF grant 2014 to participate at "Working with the parasite data base resources 2014", Cambridge, UK.
  2. Presidential award for Publications in 2008.
  3. Full grant awarded to participate at the Worldleish 5 international conference held in Brazil, 13th to 17th May 2013 to present a poster titled "Early pattern of rk39 sero-prevalence in a cutaneous leishmaniasis endemic area in Sri Lanka" by the organizers of Worldleish 5. (granted by the organizing committee Worldleish5)
  4. Travel and participation award to participate at "Theoretical and Practical Course on Molecular Biology of Leishmania" ICGEB, Trieste, Italy 24th-26th October 2012 conducted by International Centre for Molecular Biology and Biotechnology (ICGEB). (Travel grant by the NSF Sri Lanka, participation funds from ICGEB)
  5. WHO sponsored Service training programme on "Taxonomy of Phlebotomus sandflies". Department of Entomology, Medical Research Institute, Sri Lanka 17th February 2009.
  6. Won the University Grant ASP/06/RE/MED/2012/30 for the study titled "Analysis of internal transcribed spaced (ITS) sequence of RNA gene and partial sequence of 6 phosphogluconate dehydrogenase (6PGDH) gene of Leishmania DNA isolated from selected Sri Lankan patients with leishmaniasis".
  7. Won the University Grant ASP/06/RE/2008/03 for the study titled "A study to assess the prevalence of sandflies in diagnosed cutaneous leishmanisis patients habitats".