CENTRE FOR KIDNEY RESEARCH

University of Sri Jayewardenepura

 
INTRODUCTION

Kidney (renal) disease is a problem encountered throughout the world. At present Sri Lanka is faced with an increase in renal disease with Chronic Kidney Disease being the major disease. Chronic Kidney Disease (CKD) is characterized by progressive destruction of renal mass with irreversible sclerosis and loss of nephrons over a period of months to years, depending on the underlying aetiology. Yet unfortunately the incidence rates, aetiology, and demographic patterns of CKD in Sri Lanka are largely unknown as only few studies have been published on the topic. With the emergence of endemic CKD of unknown aetiology (CKDu) in the North Central Province in the 1990’s, a lot of research has been confined to the study of the aetiology of CKDu. Yet renal failure due to other causes which amounts to a large number has gone unnoticed. Due to rapid increase in diabetes mellitus in Sri Lanka and subsequent increase in diabetic nephropathy, it is predicted that the incidence of renal failure needing renal transplantation will further rise in the future, causing a huge burden to our economy and healthcare resources. Thus, it is crucial to carry out research in determining diagnostic, risk and prognostic factors as well as effective treatment modalities.

One of the greatest challenges of chronic renal disease faced in Sri Lanka is early diagnosis which could help in limiting the need for dialysis and renal transplantation, both entities being costly for the individual concerned as well as the country. Thus early detection of disease will help the individuals to be treated and managed before they go into ESRD and the country would also benefit from the monetary burden that they have to incur. This necessitates research on novel drugs which could stop or slow down the progression of kidney disease.

Research and technology development has been the key factor in development of economies such as South Korea and Singapore. Although, in Sri Lanka, there are individuals capable of carrying out highly scientific research, which would help in reducing the burden due to many diseases and policy making, funding for research has almost been non-existent in the past years. Therefore, in order to finding long lasting solutions to the increasing incidence of renal disease, novel drugs for halting disease progression and formation of policies based on scientific evidence, it would be crucial to establish a dedicated centre for research on kidney disease.

Center for kidney research was established in 2015 under the patronage of the Vice Chancellor of the University of Sri Jayewardenepura, Prof. Sampath Amaratunge and Dean Faculty of Medical Sciences, Prof. Surangi Yasawardene.

The aim of the centre is to initiate, facilitate and support basic and applied scientific research related to kidney disease by universities and conduct multidisciplinary collaborative research address themes of national importance. The centre will support numerous research, development & innovation activities/ programmes in the field of kidney disease to enhance the outputs and outcomes which will benefit the Sri Lankan society in the long run.

 
OPPORTUNITY

The University of Sri Jayewardenepura has many academics who are very research oriented and are committed to carrying out research on renal disease and function.

 
VISION, MISSION & OBJECTIVES

Vision

To carry out highly scientific, multidisciplinary research, in order to find out novel
diagnostic markers and treatment methods for kidney disease and thereby
contributing to early detection, prevention and effective treatment of patients
with kidney disease in Sri Lanka.


Mission

To contribute to the vision by providing independent, objective, and expert
scientific and medical research in the fields of biochemistry,
pathology, medicine, pharmacy, environment and social factors.

To conduct high quality research on kidney disease to promote
multidisciplinary and interdisciplinary collaborative work with
National and International Research Centers.

To create a critical mass within the University of Sri Jayewardenepura in the field of kidney disease research.


Objectives

To investigate the diagnostic value of novel markers of kidney disease in Sri Lankans and determine the, biochemical and nutritional parameters that are associated with occurrence, progression and severity of chronic kidney disease.

To investigate the factors which lead to progression of chronic kidney disease in Sri Lankans and determine new treatment modalities and explore traditional and Ayurvedic treatment modalities that are effective in treating renal disease and isolation of active ingredients

 
RESEARCH PROJECTS FUNDED THROUGH CKDR

Study on biochemical markers in CKDU funded through University research grant leading to a PhD degree.

Proposed research projects funded through CKDR

  1. Investigating the diagnostic value of novel markers of CKD factors in Sri Lankans and determining the biochemical and nutritional parameters that are associated with occurrence, progression and severity of CKD.
  2. A feasibility study to carry out clinical trials using Ayurvedic medicinal products for Kidney disease leading to a M.Phil/PhD degree program.
  3. In the process of formulating a proposal to detect Glomerular Filtration Rate (GFR) in Sri Lankans with the aim of validating eGFR measurements in Sri Lankan population.
 
SCIENTIFIC ADVISORY PANEL

Patron

     
       

Prof. Sampath Amaratunga
Vice Chancellor
University of Sri Jayewardenepura

Prof. Surangi G. Yasawardena
Dean
Faculty of Medical Sciences
University of Sri Jayewardenepura

       

Acting Director

     
       

Prof. Hemantha Peiris
Senior Professor
Department of Biochemistry
Faculty of Medical Sciences
University of Sri Jayewardenepura

   
       

Members

     
       
Prof. Pathmalal Manage
Director / Research Centres
University of Sri Jayewardenepura
Dr. Pradeepa Jayawardene
Chairperson / Research Committee
Faculty of Medical Sciences
University of Sri Jayewardenepura
       
Prof. Kamani Wanigasuriya
Professor
Department of Medicine
Faculty of Medical Sciences
University of Sri Jayewardenepura
Prof. Sugandika Suresh
Professor in Biochemistry
Department of Biochemistry
Faculty of Medical Sciences
University of Sri Jayewardenepura
       
Dr. Rasika Perera
Senior Lecturer
Department of Biochemistry
Faculty of Medical Sciences
University of Sri Jayewardenepura
Dr. Mangala Bopagoda
Department of Pathology
Faculty of Medical Sciences
University of Sri Jayewardenepura
       
Dr. Banukie Jayasuriya
Senior Lecturer
Department of Allied Health Sciences
Faculty of Medical Sciences
University of Sri Jayewardenepura
Miss. Nadeeka Ranasinghe
Co-opted Member
Faculty of Medical Sciences
University of Sri Jayewardenepura

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